Resolution:
When setting up a BusinessWorks project with multiple BC connections for different protocols (such as EDI and tibXML) using RVCM or RVCMQ, make sure that the ledger file name and CM name are unique for each connection, and not shared among the connections in the BW project.  Failure to do so will result in registration collisions, which can cause memory leaks within the BC Server that is working with the BW project, and also impact system through put.