Resolution:   First identify the SMTP setting for your Office 365 account, and then configure the Email Settings in the Console under site settings.

Identify SMPT Setting in Office 365

1. Login to your account from the web interface
2. Click on the gear menu in the top right corner, and select Options
3. Under Your app settings, select Mail
4. Under Accounts, select POP and IMAP to view the SMTP setting information

• Server name
• Port

Configure Insight Email Settings

1. Launch the TIBCO Scribe Console and navigate to Administration > Site Settings > Email Settings
2. Enter your Office 365 information in the SMTP Configuration (outbound) form

• Login Method:  Authentication
• Use SSL:  selected

3. Click <Test Send>
4. Add user to Alert Recipients, activate Alert Notification monitor, and restart the Scribe services.

Reference article:  How to grant Exchange and Outlook mailbox permissions in Office 365 dedicated

1. Ensure Alert Notification is Active.
   • In the Console, navigate to Administration > Site Settings > General.
   • In the Alert Notification section, “Notification Monitor is” Active.  If status is Paused, click <Resume>.
2. Ensure Alert Recipient notifications are selected.
   • In the Console, navigate to Administration > Alert Recipients.
   • Select the Recipient, click <Edit>, and select the Notification tab.
   • In the “Notify this email address” field, select the Alert types to send emails (ex: Critical errors, Errors, Warnings, Info messages).