Endpoint is incorrect. Re-generate endpoints.
1). Import the dat file in the Designer.
2). Change endpoint configuration for each service.
For example, change "Quality Of Service" for RV or "Delivery Mode" for JMS to recreated the endpoint.
Change the “Reply Sender Quality of Service” to another value.
3). Change back to the original configuration.
4). Export the project to a dat file or archive it into an ear file.