ApplicationSetupException at Spotfire.Dxp.Framework:
Failed to initialize extension. (HRESULT: 80131500)

Stack Trace:
   at Spotfire.Dxp.Framework.Services.GlobalServiceRegistry.GlobalServicesCreated(IServiceFactory serviceFactory, AddInManager addinManager)
   at Spotfire.Dxp.Main.Program.<>c__DisplayClass1.<StartMain>b__0()


TypeInitializationException at Spotfire.Dxp.Data.Adapters.Vertica:
The type initializer for 'Spotfire.Dxp.Data.Adapters.Vertica.VerticaAdapterFactory' threw an exception. (HRESULT: 80131534)

Stack Trace:
   at Spotfire.Dxp.Data.Adapters.Vertica.VerticaAdapterFactory..ctor()
   at Spotfire.Dxp.Data.Adapters.Vertica.VerticaAdapterAddIn.RegisterDataAdapters(DataAdapterRegistrar registrar)
   at Spotfire.Dxp.Application.Extension.AddIn.Spotfire.Dxp.Framework.AddIn.IAddIn.RegisterDataAdapters(IServiceProvider serviceProvider)
   at Spotfire.Dxp.Framework.AddIn.AddInManager.Spotfire.Dxp.Framework.Services.IServiceFactory.UseGlobalServices(GlobalServiceRegistry serviceProvider)
   at Spotfire.Dxp.Framework.Services.GlobalServiceRegistry.GlobalServicesCreated(IServiceFactory serviceFactory, AddInManager addinManager)


ConfigurationErrorsException at System.Configuration:
The 'DbProviderFactories' section can only appear once per config file. (HRESULT: 80131902)

Stack Trace:
   at System.Configuration.BaseConfigurationRecord.EvaluateOne(String[] keys, SectionInput input, Boolean isTrusted, FactoryRecord factoryRecord, SectionRecord sectionRecord, Object parentResult)
   at System.Configuration.BaseConfigurationRecord.Evaluate(FactoryRecord factoryRecord, SectionRecord sectionRecord, Object parentResult, Boolean getLkg, Boolean getRuntimeObject, Object& result, Object& resultRuntimeObject)
   at System.Configuration.BaseConfigurationRecord.GetSectionRecursive(String configKey, Boolean getLkg, Boolean checkPermission, Boolean getRuntimeObject, Boolean requestIsHere, Object& result, Object& resultRuntimeObject)
   at System.Configuration.BaseConfigurationRecord.GetSectionRecursive(String configKey, Boolean getLkg, Boolean checkPermission, Boolean getRuntimeObject, Boolean requestIsHere, Object& result, Object& resultRuntimeObject)
   at System.Configuration.BaseConfigurationRecord.GetSectionRecursive(String configKey, Boolean getLkg, Boolean checkPermission, Boolean getRuntimeObject, Boolean requestIsHere, Object& result, Object& resultRuntimeObject)
   at System.Configuration.BaseConfigurationRecord.GetSectionRecursive(String configKey, Boolean getLkg, Boolean checkPermission, Boolean getRuntimeObject, Boolean requestIsHere, Object& result, Object& resultRuntimeObject)
   at System.Configuration.BaseConfigurationRecord.GetSection(String configKey)
   at System.Configuration.ConfigurationManager.GetSection(String sectionName)
   at System.Configuration.PrivilegedConfigurationManager.GetSection(String sectionName)
   at System.Data.Common.DbProviderFactories.Initialize()
   at System.Data.Common.DbProviderFactories.GetFactoryClasses()
   at Spotfire.Dxp.Data.Adapters.Vertica.VerticaAdapterFactory.GetInstalledVerticaDriverAssembly()
   at Spotfire.Dxp.Data.Adapters.Vertica.VerticaAdapterFactory..cctor()

• The 'DbProviderFactories' section can only appear once per config file

OPTION 1:

Check the following file:

• C:\Windows\Microsoft.NET\Framework\v4.0.30319\Config\Machine.Config

The block to pay attention to is this:

<system.data>
        <DbProviderFactories>
            <add name="IBM DB2 for i5/OS .NET Provider" invariant="IBM.Data.DB2.iSeries" description=".NET Framework Data Provider for i5/OS" type="IBM.Data.DB2.iSeries.iDB2Factory, IBM.Data.DB2.iSeries, Version=12.0.0.0, Culture=neutral, PublicKeyToken=9cdb2ebfb1f93a26"/>
            <add name="Microsoft SQL Server Compact Data Provider" invariant="System.Data.SqlServerCe.3.5" description=".NET Framework Data Provider for Microsoft SQL Server Compact" type="System.Data.SqlServerCe.SqlCeProviderFactory, System.Data.SqlServerCe, Version=3.5.0.0, Culture=neutral, PublicKeyToken=89845dcd8080cc91"/>
       </DbProviderFactories>
       <DbProviderFactories/>
    </system.data>

In the machine.config file under the V4.0.30319 folder, look for lines like (note that there are two separate DbProviderFactories nodes, one with data and one empty node):

<system.data>
         ...
        <DbProviderFactories />
   </system.data>

Delete this line only (the empty DbProviderFactories node):

<DbProviderFactories />

Close and save the file. 

For example, the above block when modified correctly would look like the following:

<system.data>
        <DbProviderFactories>
            <add name="IBM DB2 for i5/OS .NET Provider" invariant="IBM.Data.DB2.iSeries" description=".NET Framework Data Provider for i5/OS" type="IBM.Data.DB2.iSeries.iDB2Factory, IBM.Data.DB2.iSeries, Version=12.0.0.0, Culture=neutral, PublicKeyToken=9cdb2ebfb1f93a26"/>
            <add name="Microsoft SQL Server Compact Data Provider" invariant="System.Data.SqlServerCe.3.5" description=".NET Framework Data Provider for Microsoft SQL Server Compact" type="System.Data.SqlServerCe.SqlCeProviderFactory, System.Data.SqlServerCe, Version=3.5.0.0, Culture=neutral, PublicKeyToken=89845dcd8080cc91"/>
       </DbProviderFactories>
    </system.data>

Then attempt to install TIBCO Spotfire Desktop again.

OPTION 2:

Uninstall Microsoft .NET completely from your computer and then reinstall just the latest version from Microsoft.

• http://forums.asp.net/t/1693277.aspx/1