For the 7.0 Spotfire Professional client, after doing an upgrade or fresh install, users can see the initial landing page. However, after opening an analysis the page is blank. There are no visualizations or no errors.

Newly installed TIBCO Spotfire 7.0.x (desktop client / Analyst / Professional) does not display visualizations.

First verify the following general troubleshooting steps were performed:
 - Previous Spotfire client would work on the same computer; after an upgrade this symptom will be seen.
 - Previous version of Spotfire worked OK on the computer.
 - System requirements are met, both for the .Net Framework version and IE.
 - A clean installation of the client was performed.
 - Confirmed the issue is specific to a computer.
 - The .Net 4.5.x Framework was repaired and the newest version installed.
 - No errors reported in the logs.

Then you can perform this step in Internet Explorer 10/11 to potentially resolve the issue:
 - Go to Internet Explorer's Tools->Options->Advanced (tab).
 - "Resets Internet Explorer's settings to their default conditions" > Click the "Reset" button
 - Restart the Spotfire client.