After installing TIBCO Spotfire Desktop (standalone version) to the default location, the "%localappdata%\TIBCO\Spotfire Desktop\x.x.x" folder, you can then move the installation folder to wherever you like, for example, the "C:\Program Files\" folder.

There is one file in the installation folder that needs to be edited to reflect the new installation path. Edit the "Spotfire.Dxp.exe.config" file located in the installation folder and replace the path in the "<folder path="C:\Users\USERNAME\AppData\Local\TIBCO\Spotfire Desktop\X.X.X\Modules"/>" to point to the new location of the installation folder.

During the installation, a shortcut will be created on your desktop, so you will have to manually edit that, or you can delete it and create your own. The shortcut needs to be created in "C:\Users\USERNAME\AppData\Roaming\Microsoft\Windows\Start Menu\Programs\TIBCO".